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apalutamide will decrease the level or effect of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Coadministration of apalutamide, a robust CYP3A4 inducer, with medications which might be CYP3A4 substrates can result in decreased publicity to those prescription drugs.Antihistamines: concomitan

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